A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

The Delta–Notch signal transduction pathway has widespread roles in animal development in which it appears to control cell fate. CBF1/RBP-Jκ, the mammalian homolog of Drosophila Suppressor of Hairless [Su(H)], switches from a transcriptional repressor to an activator upon Notch activation. The mecha...

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Main Authors: Kao, Hung-Ying, Ordentlich, Peter, Koyano-Nakagawa, Naoko, Tang, Zhenyu, Downes, Michael, Kintner, Chris R., Evans, Ronald M., Kadesch, Tom
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 1998
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC317043/
https://ncbi.nlm.nih.gov/pubmed/9694793
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