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Worsening of Cardiomyopathy Using Deflazacort in an Animal Model Rescued by Gene Therapy

We have previously demonstrated that gene therapy can rescue the phenotype and extend lifespan in the delta-sarcoglycan deficient cardiomyopathic hamster. In patients with similar genetic defects, steroids have been largely used to slow down disease progression. Aim of our study was to evaluate the...

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Autors principals: Rotundo, Ida Luisa, Faraso, Stefania, De Leonibus, Elvira, Nigro, Gerardo, Vitiello, Carmen, Lancioni, Alessio, Di Napoli, Daniele, Castaldo, Sigismondo, Russo, Vincenzo, Russo, Fabio, Piluso, Giulio, Auricchio, Alberto, Nigro, Vincenzo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170375/
https://ncbi.nlm.nih.gov/pubmed/21931833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024729
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