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c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

The c-Abl tyrosine kinase localizes to the cytoplasm and plasma membrane in addition to the nucleus. However, there is little information regarding a role for c-Abl in the cytoplasm/plasma membrane compartments. Here we report that a membrane pool of c-Abl is activated by the growth factors PDGF and...

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Autori principali: Plattner, Rina, Kadlec, Lisa, DeMali, Kris A., Kazlauskas, Andrius, Pendergast, Ann Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC317022/
https://ncbi.nlm.nih.gov/pubmed/10500097
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