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Multicomponent synthesis of artificial nucleases and their RNase and DNase activity

The synthesis of new, artificial ribonucleases containing two amino acid residues connected by an aliphatic linker has been developed. Target molecules were synthesized via a catalytic three-component Ugi reaction from aliphatic diisocyanides. Preliminary investigations proved unspecific nuclease ac...

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מידע ביבליוגרפי
Main Authors: Gulevich, Anton V, Koroleva, Lyudmila S, Morozova, Olga V, Bakhvalova, Valentina N, Silnikov, Vladimir N, Nenajdenko, Valentine G
פורמט: Artigo
שפה:Inglês
יצא לאור: Beilstein-Institut 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170195/
https://ncbi.nlm.nih.gov/pubmed/21915218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.131
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