A zinc-binding site in the largest subunit of DNA-dependent RNA polymerase is involved in enzyme assembly

All multisubunit DNA-dependent RNA polymerases (RNAP) are zinc metalloenzymes, and at least two zinc atoms are present per enzyme molecule. RNAP residues involved in zinc binding and the functional role of zinc ions in the transcription mechanism or RNAP structure are unknown. Here, we locate four c...

Description complète

Détails bibliographiques

Publié dans:	Genes Dev
Auteurs principaux:	Markov, Dmitriy, Naryshkina, Tatyana, Mustaev, Arkady, Severinov, Konstantin
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 1999
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.18.2439
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!