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Determinants of specificity in TGF-β signal transduction

Signal transduction by the TGF-β family involves sets of receptor serine/threonine kinases, Smad proteins that act as receptor substrates, and Smad-associated transcription factors that target specific genes. We have identified discrete structural elements that dictate the selective interactions bet...

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Détails bibliographiques
Auteurs principaux: Chen, Ye-Guang, Hata, Akiko, Lo, Roger S., Wotton, David, Shi, Yigong, Pavletich, Nikola, Massagué, Joan
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC317013/
https://ncbi.nlm.nih.gov/pubmed/9679059
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