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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.
Signal transduction specificity in the transforming growth factor-beta (TGF-beta) system is determined by ligand activation of a receptor complex which then recruits and phosphorylates a subset of SMAD proteins including Smads 1 and 2. These then associate with Smad4 and move into the nucleus where...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170449/ https://ncbi.nlm.nih.gov/pubmed/9463378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.996 |
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