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Mutation Rates across Budding Yeast Chromosome VI Are Correlated with Replication Timing

Previous experimental studies suggest that the mutation rate is nonuniform across the yeast genome. To characterize this variation across the genome more precisely, we measured the mutation rate of the URA3 gene integrated at 43 different locations tiled across Chromosome VI. We show that mutation r...

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Detalhes bibliográficos
Main Authors: Lang, Gregory I., Murray, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170098/
https://ncbi.nlm.nih.gov/pubmed/21666225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr054
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