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The Role of Replication Bypass Pathways in Dicentric Chromosome Formation in Budding Yeast

Gross chromosomal rearrangements (GCRs) are large scale changes to chromosome structure and can lead to human disease. We previously showed in Saccharomyces cerevisiae that nearby inverted repeat sequences (∼20–200 bp of homology, separated by ∼1–5 kb) frequently fuse to form unstable dicentric and...

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Autors principals: Paek, Andrew L., Jones, Hope, Kaochar, Salma, Weinert, Ted
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998301/
https://ncbi.nlm.nih.gov/pubmed/20837992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.122663
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