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The Role of Replication Bypass Pathways in Dicentric Chromosome Formation in Budding Yeast
Gross chromosomal rearrangements (GCRs) are large scale changes to chromosome structure and can lead to human disease. We previously showed in Saccharomyces cerevisiae that nearby inverted repeat sequences (∼20–200 bp of homology, separated by ∼1–5 kb) frequently fuse to form unstable dicentric and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998301/ https://ncbi.nlm.nih.gov/pubmed/20837992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.122663 |
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