Prostaglandin E2 and IL‐23 plus IL‐1β Differentially Regulate the Th1/Th17 Immune Response of Human CD161(+)CD4(+) Memory T Cells

Prostaglandin E2 (PGE2), interleukin (IL)‐23, and IL‐1beta (β) propagate inflammatory bowel disease (IBD) by enhancing the development and function of IL‐17 producing CD4(+) T helper (Th17) cells. CD4(+) T cells that express the C‐type lectin‐like receptor CD161 have been proposed to be the physiolo...

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Detalhes bibliográficos
Main Authors: Barrie, Arthur, Khare, Anupriya, Henkel, Matthew, Zhang, Yingze, Barmada, M. Michael, Duerr, Richard, Ray, Anuradha
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170085/
https://ncbi.nlm.nih.gov/pubmed/21884514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2011.00300.x
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