Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections

IL-22 is a member of the IL-10 cytokine family and signals through a heterodimeric receptor composed of the common IL-10R2 subunit and the IL-22R subunit. IL-10 and IL-22 both activate the STAT3 signaling pathway; however, in contrast to IL-10, relatively little is known about IL-22 in the host resp...

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Main Authors: Wilson, Mark S., Feng, Carl G., Barber, Daniel L., Yarovinsky, Felix, Cheever, Allen W., Sher, Alan, Grigg, Michael, Collins, Mary, Fouser, Lynette, Wynn, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170015/
https://ncbi.nlm.nih.gov/pubmed/20220096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903416
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