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Cost–utility analysis of prophylaxis versus treatment on demand in severe hemophilia A

BACKGROUND: Individuals with severe hemophilia A have reduced blood levels of clotting factor VIII (FVIII) leading to recurrent bleeding into joints and muscles. Primary prophylaxis with clotting factor concentrates started early in childhood prevents joint bleeds, thus avoiding joint damage and imp...

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Autors principals: Colombo, Giorgio L, Di Matteo, Sergio, Mancuso, Maria Elisa, Santagostino, Elena
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169977/
https://ncbi.nlm.nih.gov/pubmed/21935333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEOR.S16670
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