Cost–utility analysis of prophylaxis versus treatment on demand in severe hemophilia A

BACKGROUND: Individuals with severe hemophilia A have reduced blood levels of clotting factor VIII (FVIII) leading to recurrent bleeding into joints and muscles. Primary prophylaxis with clotting factor concentrates started early in childhood prevents joint bleeds, thus avoiding joint damage and imp...

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Bibliographic Details
Main Authors: Colombo, Giorgio L, Di Matteo, Sergio, Mancuso, Maria Elisa, Santagostino, Elena
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2011
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169977/
https://ncbi.nlm.nih.gov/pubmed/21935333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEOR.S16670
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