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Epistatic Selection between Coding and Regulatory Variation in Human Evolution and Disease
Interaction (nonadditive effects) between genetic variants has been highlighted as an important mechanism underlying phenotypic variation, but the discovery of genetic interactions in humans has proved difficult. In this study, we show that the spectrum of variation in the human genome has been shap...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169828/ https://ncbi.nlm.nih.gov/pubmed/21907014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.08.004 |
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