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A General Framework for Detecting Disease Associations with Rare Variants in Sequencing Studies
Biological and empirical evidence suggests that rare variants account for a large proportion of the genetic contributions to complex human diseases. Recent technological advances in high-throughput sequencing platforms have made it possible for researchers to generate comprehensive information on ra...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169821/ https://ncbi.nlm.nih.gov/pubmed/21885029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.07.015 |
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