CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma

We previously reported that scavenger receptor A (SRA/CD204), a binding structure on dendritic cells (DCs) for large stress/heat shock proteins (HSPs, e.g., hsp110 and grp170), attenuated an antitumor response elicited by large HSP-based vaccines. Here we show that SRA/CD204 interacts directly with...

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Main Authors: Qian, Jie, Yi, Huanfa, Guo, Chunqing, Yu, Xiaofei, Zuo, Daming, Chen, Xing, Kane, John, Repasky, Elizabeth, Subjeck, John, Wang, Xiang-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169704/
https://ncbi.nlm.nih.gov/pubmed/21832164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100703
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