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The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survival

Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express an onconeural antigen termed cdr2, which normally is expressed in cerebellar Purkinje neurons. This leads to an immune response to cdr2 that is associated with tumor immunity and autoimmune cerebella...

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Autors principals: Okano, Hirotaka J., Park, Woong-Y., Corradi, John P., Darnell, Robert B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316965/
https://ncbi.nlm.nih.gov/pubmed/10465786
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