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Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles

To become infectious, HIV-1 particles undergo a maturation process involving proteolytic cleavage of the Gag and Gag-Pol polyproteins. Immature particles contain a highly stable spherical Gag lattice and are impaired for fusion with target cells. The fusion impairment is relieved by truncation of th...

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Bibliografske podrobnosti
Main Authors: Joyner, Amanda S., Willis, Jordan R., Crowe, James E., Aiken, Christopher
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169560/
https://ncbi.nlm.nih.gov/pubmed/21931551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002234
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