Disruption of TLR3 Signaling Due to Cleavage of TRIF by the Hepatitis A Virus Protease-Polymerase Processing Intermediate, 3CD

Toll-like receptor 3 (TLR3) and cytosolic RIG-I-like helicases (RIG-I and MDA5) sense viral RNAs and activate innate immune signaling pathways that induce expression of interferon (IFN) through specific adaptor proteins, TIR domain-containing adaptor inducing interferon-β (TRIF), and mitochondrial a...

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Bibliografiske detaljer
Main Authors: Qu, Lin, Feng, Zongdi, Yamane, Daisuke, Liang, Yuqiong, Lanford, Robert E., Li, Kui, Lemon, Stanley M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169542/
https://ncbi.nlm.nih.gov/pubmed/21931545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002169
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