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Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II

Transcriptome dynamics is governed by two opposing processes, mRNA production and degradation. Recent studies found that changes in these processes are frequently coordinated and that the relationship between them shapes transcriptome kinetics. Specifically, when transcription changes are counter-ac...

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Autori principali: Shalem, Ophir, Groisman, Bella, Choder, Mordechai, Dahan, Orna, Pilpel, Yitzhak
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169527/
https://ncbi.nlm.nih.gov/pubmed/21931566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002273
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