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Structure of thymidylate kinase from Ehrlichia chaffeensis

The enzyme thymidylate kinase phosphorylates the substrate thymidine 5′-­phosphate (dTMP) to form thymidine 5′-diphosphate (dTDP), which is further phosphorylated to dTTP for incorporation into DNA. Ehrlichia chaffeensis is the etiologic agent of human monocytotropic erlichiosis (HME), a potentially...

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Detalhes bibliográficos
Main Authors: Leibly, David J., Abendroth, Jan, Bryan, Cassie M., Sankaran, Banumathi, Kelley, Angela, Barrett, Lynn K., Stewart, Lance, Van Voorhis, Wesley C.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169407/
https://ncbi.nlm.nih.gov/pubmed/21904055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911101493X
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