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Possible Mechanisms of Local Tissue Renin-Angiotensin System Activation in the Cardiorenal Metabolic Syndrome and Type 2 Diabetes Mellitus

The role of local tissue renin-angiotensin system (tRAS) activation in the cardiorenal metabolic syndrome (CRS) and type 2 diabetes mellitus (T2DM) is not well understood. To this point, we posit that early redox stress-mediated injury to tissues and organs via accumulation of excessive reactive oxy...

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Autors principals: Hayden, Melvin R., Sowers, Kurt M., Pulakat, Lakshmi, Joginpally, Tejaswini, Krueger, Bennett, Whaley-Connell, Adam, Sowers, James R.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169372/
https://ncbi.nlm.nih.gov/pubmed/22096455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000329926
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