Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation

Thymic stromal lymphopoetin (TSLP) influences numerous immune functions, including those in the colonic mucosa. Here we report that TSLP-deficient (Tslp(-/-)) mice, did not exhibit increased inflammation during dextran sodium sulfate (DSS)-induced colitis, but failed to recover from disease, resulti...

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Détails bibliographiques
Auteurs principaux: Reardon, Colin, Lechmann, Matthias, Brüstle, Anne, Gareau, Mélanie G, Shuman, Naomi, Philpott, Dana, Ziegler, Steven F., Mak, Tak W
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169330/
https://ncbi.nlm.nih.gov/pubmed/21820333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.015
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