Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation

Thymic stromal lymphopoetin (TSLP) influences numerous immune functions, including those in the colonic mucosa. Here we report that TSLP-deficient (Tslp(-/-)) mice, did not exhibit increased inflammation during dextran sodium sulfate (DSS)-induced colitis, but failed to recover from disease, resulti...

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Main Authors: Reardon, Colin, Lechmann, Matthias, Brüstle, Anne, Gareau, Mélanie G, Shuman, Naomi, Philpott, Dana, Ziegler, Steven F., Mak, Tak W
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169330/
https://ncbi.nlm.nih.gov/pubmed/21820333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.05.015
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