A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase
Inactivation of cyclin B–Cdc2 kinase at the exit from M phase depends on the specific proteolysis of the cyclin B subunit, whereas the Cdc2 subunit remains present at nearly constant levels throughout the cell cycle. It is unknown how Cdc2 escapes degradation when cyclin B is destroyed. In Xenopus e...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10995390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.823200 |
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