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The Inside-Out Mechanism of Dicers from Budding Yeasts

The Dicer ribonuclease III (RNase III) enzymes process long double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) that direct RNA interference. Here, we describe the structure and activity of a catalytically active fragment of Kluyveromyces polysporus Dcr1, which represents the noncanonic...

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Bibliografski detalji
Glavni autori: Weinberg, David E., Nakanishi, Kotaro, Patel, Dinshaw J., Bartel, David P.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169304/
https://ncbi.nlm.nih.gov/pubmed/21784247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.021
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