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The Inside-Out Mechanism of Dicers from Budding Yeasts
The Dicer ribonuclease III (RNase III) enzymes process long double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) that direct RNA interference. Here, we describe the structure and activity of a catalytically active fragment of Kluyveromyces polysporus Dcr1, which represents the noncanonic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169304/ https://ncbi.nlm.nih.gov/pubmed/21784247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.021 |
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