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HLA-Ig Based Artificial Antigen Presenting Cells for Efficient ex vivo Expansion of Human CTL

CTL with optimal effector function play critical roles in mediating protection against various intracellular infections and cancer. However, individuals may exhibit suppressive immune microenvironment and, in contrast to activating CTL, their autologous antigen presenting cells may tend to tolerize...

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Autori principali: Chiu, Yen-Ling, Schneck, Jonathan P., Oelke, Mathias
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169282/
https://ncbi.nlm.nih.gov/pubmed/21505415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2801
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