Enrichment and Expansion with Nano-Artificial Antigen Presenting Cells for Adoptive Immunotherapy

Adoptive immunotherapy (AIT) can mediate durable regression of cancer, but widespread adoption of AIT is limited by the cost and complexity of generating tumor-specific T cells. Here we develop an Enrichment + Expansion strategy using paramagnetic, nanoscale artificial Antigen Presenting Cells (aAPC...

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Publicado en:ACS Nano
Autores principales: Perica, Karlo, Bieler, Joan Glick, Schütz, Christian, Varela, Juan Carlos, Douglass, Jacqueline, Skora, Andrew, Chiu, Yen Ling, Oelke, Mathias, Kinzler, Kenneth, Zhou, Shibin, Vogelstein, Bert, Schneck, Jonathan P
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082131/
https://ncbi.nlm.nih.gov/pubmed/26171764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b02829
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