Enrichment and Expansion with Nano-Artificial Antigen Presenting Cells for Adoptive Immunotherapy

Adoptive immunotherapy (AIT) can mediate durable regression of cancer, but widespread adoption of AIT is limited by the cost and complexity of generating tumor-specific T cells. Here we develop an Enrichment + Expansion strategy using paramagnetic, nanoscale artificial Antigen Presenting Cells (aAPC...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Perica, Karlo, Bieler, Joan Glick, Schütz, Christian, Varela, Juan Carlos, Douglass, Jacqueline, Skora, Andrew, Chiu, Yen Ling, Oelke, Mathias, Kinzler, Kenneth, Zhou, Shibin, Vogelstein, Bert, Schneck, Jonathan P
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082131/
https://ncbi.nlm.nih.gov/pubmed/26171764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b02829
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