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Derivation of Thymic Lymphoma T-cell Lines from Atm(-/-) and p53(-/-) Mice

Established cell lines are a critical research tool that can reduce the use of laboratory animals in research. Certain strains of genetically modified mice, such as Atm(-/-) and p53(-/-) consistently develop thymic lymphoma early in life (1,2), and thus, can serve as a reliable source for derivation...

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Detalhes bibliográficos
Main Authors: Jinadasa, Rasika, Balmus, Gabriel, Gerwitz, Lee, Roden, Jamie, Weiss, Robert, Duhamel, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169248/
https://ncbi.nlm.nih.gov/pubmed/21490582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2598
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