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Derivation of Thymic Lymphoma T-cell Lines from Atm(-/-) and p53(-/-) Mice
Established cell lines are a critical research tool that can reduce the use of laboratory animals in research. Certain strains of genetically modified mice, such as Atm(-/-) and p53(-/-) consistently develop thymic lymphoma early in life (1,2), and thus, can serve as a reliable source for derivation...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MyJove Corporation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169248/ https://ncbi.nlm.nih.gov/pubmed/21490582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2598 |
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