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A novel property of the RecA nucleoprotein filament: activation of double- stranded DNA for strand exchange in trans

RecA protein catalyzes DNA strand exchange, a basic step of homologous recombination. Upon binding to single-stranded DNA (ssDNA), RecA protein forms a helical nucleoprotein filament. Normally, this nucleoprotein filament binds double-stranded DNA (dsDNA) and promotes exchange of base pairs between...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mazin, Alexander V., Kowalczykowski, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316918/
https://ncbi.nlm.nih.gov/pubmed/10444598
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