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The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4
Cells can respond to mechanical stress by gating mechanosensitive ion channels (MSCs). The cloning of Piezo1, a eukaryotic cation-selective MSC, defines a new system to study mechanical transduction at the cellular level. Since Piezo1 has electrophysiological properties similar to endogenous cationi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169095/ https://ncbi.nlm.nih.gov/pubmed/21696149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200770q |
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