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The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4

Cells can respond to mechanical stress by gating mechanosensitive ion channels (MSCs). The cloning of Piezo1, a eukaryotic cation-selective MSC, defines a new system to study mechanical transduction at the cellular level. Since Piezo1 has electrophysiological properties similar to endogenous cationi...

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Hlavní autoři: Bae, Chilman, Sachs, Frederick, Gottlieb, Philip A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169095/
https://ncbi.nlm.nih.gov/pubmed/21696149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200770q
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