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Axotomy induces axonogenesis in hippocampal neurons through STAT3

After axotomy of embryonic hippocampal neurons in vitro, some of the axotomized axons lose their identity, and new axons arise and grow. This axotomy-induced axonogenesis requires importin, suggesting that some injury-induced signals are transported via axons to elicit axonogenesis after axotomy. In...

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Autori principali: Ohara, R, Fujita, Y, Hata, K, Nakagawa, M, Yamashita, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169001/
https://ncbi.nlm.nih.gov/pubmed/21697950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.59
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