Interaction Between Troponin and Myosin Enhances Contractile Activity of Myosin in Cardiac Muscle

Ca(2+) signaling in striated muscle cells is critically dependent upon thin filament proteins tropomyosin (Tm) and troponin (Tn) to regulate mechanical output. Using in vitro measurements of contractility, we demonstrate that even in the absence of actin and Tm, human cardiac Tn (cTn) enhances heavy...

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Detalhes bibliográficos
Main Authors: Schoffstall, Brenda, LaBarbera, Vincent A., Brunet, Nicolas M., Gavino, Belinda J., Herring, Lauren, Heshmati, Sara, Kraft, Brittany H., Inchausti, Vanessa, Meyer, Nancy L., Moonoo, Danamarie, Takeda, Aya K., Chase, Prescott Bryant
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Original Research Articles Highlighting Undergraduate Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168976/
https://ncbi.nlm.nih.gov/pubmed/21438758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2010.1163
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