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Antagonism between G(o)α and G(q)α in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)α signaling and regulates G(q)α activity
To elucidate the cellular role of the heterotrimeric G protein G(o), we have taken a molecular genetic approach in Caenorhabditis elegans. We screened for suppressors of activated GOA-1 (G(o)α) that do not simply decrease its expression and found mutations in only two genes, sag-1 and eat-16. Animal...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
1999
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316886/ https://ncbi.nlm.nih.gov/pubmed/10421631 |
| タグ: |
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