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Systematic profiling of Caenorhabditis elegans locomotive behaviors reveals additional components in G-protein Gαq signaling

Genetic screens have been widely applied to uncover genetic mechanisms of movement disorders. However, most screens rely on human observations of qualitative differences. Here we demonstrate the application of an automatic imaging system to conduct a quantitative screen for genes regulating the loco...

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Détails bibliographiques
Auteurs principaux: Yu, Hui, Aleman-Meza, Boanerges, Gharib, Shahla, Labocha, Marta K., Cronin, Christopher J., Sternberg, Paul W., Zhong, Weiwei
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718121/
https://ncbi.nlm.nih.gov/pubmed/23818641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310468110
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