In vivo and in vitro function of human UDP-galactose 4′-epimerase variants

Type III galactosemia results from reduced activity of the enzyme UDP-galactose 4′-epimerase. Five disease-associated alleles (G90E, V94M, D103G, N34S and L183P) and three artificial alleles (Y105C, N268D, and M284K) were tested for their ability to alleviate galactose-induced growth arrest in a Sac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McCorvie, Thomas J., Wasilenko, Jamie, Liu, Ying, Fridovich-Keil, Judith L., Timson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Editions Scientifiques Elsevier 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168732/
https://ncbi.nlm.nih.gov/pubmed/21703329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2011.06.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados