UDP-Galactose 4′-Epimerase Activities toward UDP-Gal and UDP-GalNAc Play Different Roles in the Development of Drosophila melanogaster

In both humans and Drosophila melanogaster, UDP-galactose 4′-epimerase (GALE) catalyzes two distinct reactions, interconverting UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) in the final step of the Leloir pathway of galactose metabolism, and also interconverting UDP-N-acetylgalactosamine (UDP-g...

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Autors principals: Daenzer, Jennifer M. I., Sanders, Rebecca D., Hang, Darwin, Fridovich-Keil, Judith L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359975/
https://ncbi.nlm.nih.gov/pubmed/22654673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002721
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