Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP

Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that cleaves precursor tRNA transcripts to give mature 5′ ends. RNase P in eubacteria has a large, catalytic RNA subunit and a small protein subunit that are required for precursor tRNA cleavage in vivo. Although the eukaryotic holoenzymes have...

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Pubblicato in:	Genes Dev
Autori principali:	Chamberlain, Joel R., Lee, Yoon, Lane, William S., Engelke, David R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 1998
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316871/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1678
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