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Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP

Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that cleaves precursor tRNA transcripts to give mature 5′ ends. RNase P in eubacteria has a large, catalytic RNA subunit and a small protein subunit that are required for precursor tRNA cleavage in vivo. Although the eukaryotic holoenzymes have...

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Detalhes bibliográficos
Publicado no:Genes Dev
Principais autores: Chamberlain, Joel R., Lee, Yoon, Lane, William S., Engelke, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316871/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620854/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1678
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