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Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity

Increased susceptibility to infections, particularly respiratory viral infections, is a hallmark of advancing age. The underlying mechanisms are not well understood, and there is a scarcity of information regarding the contribution of the innate immune system, which is the first line of defense agai...

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Main Authors: Sridharan, Aishwarya, Esposo, Marc, Kaushal, Khushboo, Tay, Jia, Osann, Kathyrn, Agrawal, Sudhanshu, Gupta, Sudhir, Agrawal, Anshu
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168606/
https://ncbi.nlm.nih.gov/pubmed/20953722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-010-9191-3
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