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Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production

The purpose of this study was to determine changes in klotho, endothelin (ET) receptors, and superoxide production in kidneys of aged rats and whether these changes are exacerbated in aged rats with cognitive impairment. Twenty aged rats (male, 27 months) were divided into an Old Impaired group (n =...

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Autori principali: Zuo, Zhong, Lei, Han, Wang, Xiuqing, Wang, Yuhong, Sonntag, William, Sun, Zhongjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168600/
https://ncbi.nlm.nih.gov/pubmed/20830528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-010-9176-2
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