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The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast

DDC2 is a novel component of the DNA integrity checkpoint pathway, which is required for proper checkpoint response to DNA damage and to incomplete DNA replication. Moreover, Ddc2 overproduction causes sensitivity to DNA-damaging agents and checkpoint defects. Ddc2 physically interacts with Mec1 and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Paciotti, Vera, Clerici, Michela, Lucchini, Giovanna, Longhese, Maria Pia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC316858/
https://ncbi.nlm.nih.gov/pubmed/10950868
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