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Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development

Gastrulation in mice is associated with the start of extreme proliferation and differentiation. The potential cost to the embryo of a very rapid proliferation rate is a high production of damaged cells. We demonstrate a novel surveillance mechanism for the elimination of cells damaged by ionizing ra...

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Bibliografski detalji
Glavni autori: Heyer, Babette S., MacAuley, Alasdair, Behrendtsen, Ole, Werb, Zena
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2000
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316856/
https://ncbi.nlm.nih.gov/pubmed/10950870
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