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Maternal DNA hypomethylation and congenital heart defects

BACKGROUND: Congenital heart defects (CHDs) are among the most prevalent and serious of birth defects. Multiple maternal factors are thought to contribute to CHD development including folate intake. Maternal DNA methylation, which is dependent on folate metabolism, may impact the risk of CHDs. OBJEC...

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Main Authors: Chowdhury, Shimul, Cleves, Mario A., MacLeod, Stewart L., James, S. Jill, Zhao, Weizhi, Hobbs, Charlotte A.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168545/
https://ncbi.nlm.nih.gov/pubmed/21254366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20761
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