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Maternal Folate-Related Gene Environment Interactions and Congenital Heart Defects

OBJECTIVE: To investigate whether women with congenital heart defect (CHD)-affected pregnancies were more likely to have functional single nucleotide polymorphisms (SNPs) in genes encoding enzymes in folate-dependent pathways. METHODS: A population-based case-control study of 572 women with CHD-affe...

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Main Authors: Hobbs, Charlotte A., Cleves, Mario A., Karim, Mohammad A., Zhao, Weizhi, MacLeod, Stewart L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027124/
https://ncbi.nlm.nih.gov/pubmed/20664391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AOG.0b013e3181e80979
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