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The control of trunk Hox specificity and activity by Extradenticle

We characterize a 37-bp element (fkh[250]) derived from the fork head (fkh) gene, a natural target of the Hox gene Sex combs reduced (Scr). In vitro, Scr cooperatively binds to this DNA with the Hox cofactor Extradenticle (Exd), and the activation of this enhancer in vivo requires Scr and exd. Other...

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Détails bibliographiques
Auteurs principaux: Ryoo, Hyung Don, Mann, Richard S.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC316852/
https://ncbi.nlm.nih.gov/pubmed/10398683
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