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Synthetic long oligonucleotides to generate artificial templates for use as positive controls in molecular assays: drug resistance mutations in influenza virus as an example

BACKGROUND: Positive controls are an integral component of any sensitive molecular diagnostic tool, but this can be affected, if several mutations are being screened in a scenario of a pandemic or newly emerging disease where it can be difficult to acquire all the necessary positive controls from th...

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Detalhes bibliográficos
Main Authors: Wang, Bin, Steain, Megan C, Dwyer, Dominic E, Cunningham, Anthony L, Saksena, Nitin K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168426/
https://ncbi.nlm.nih.gov/pubmed/21843374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-405
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