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Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription

Transcription is regulated by acetylation/deacetylation reactions of histone and nonhistone proteins mediated by enzymes called KATs and HDACs, respectively. As a major mechanism of transcriptional regulation, protein acetylation is a key controller of physiological processes such as cell cycle, DNA...

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Detalhes bibliográficos
Main Authors: Rajendran, Ramkumar, Garva, Richa, Krstic-Demonacos, Marija, Demonacos, Constantinos
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168296/
https://ncbi.nlm.nih.gov/pubmed/21912480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/368276
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