5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

We have investigated the role of the RNA Polymerase II (Pol II) carboxy-terminal domain (CTD) in mRNA 5′ capping. Transcripts made in vivo by Pol II with a truncated CTD had a lower proportion of capped 5′ ends than those made by Pol II with a full-length CTD. In addition, the enzymes responsible fo...

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Bibliografiske detaljer
Main Authors: McCracken, Susan, Fong, Nova, Rosonina, Emanuel, Yankulov, Krassimir, Brothers, Greg, Siderovski, David, Hessel, Andrew, Foster, Stephen, Program, Amgen EST, Shuman, Stewart, Bentley, David L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316822/
https://ncbi.nlm.nih.gov/pubmed/9407024
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